the turnover number for an enzyme is known to be 5000 min-1. From the following set of data, compute the Km and the total amount of enzyme present int these experiments.Substrate concentration (mM) Initial velocity (\mumol/min)1 1672 2504 3346 376100 4981000 499a.) Vmax for the enzyme is _____________. briefly explain how you determined Vmaxb.) Km for the enzyme is _______________. brielfy explan how you determined Km.c.) Total enzyme= ______________\mumol.

Answers

Answer 1

Vmax = 499 μmol/min, Km = 2.34 mM, Total enzyme = 99.8 μmol.

What is the Vmax, Km, and total amount of enzyme present given substrate concentration and initial velocity data with a turnover number of 5000 min-1?

To determine Vmax, we need to find the maximum initial velocity of the enzyme at saturating substrate concentration. From the given data, we can observe that the initial velocity reaches a plateau at substrate concentrations higher than 1000 mM.

Therefore, we can assume that the maximum initial velocity of the enzyme occurs at 4981 mM substrate concentration. Therefore,

Vmax = 499 μmol/min

To determine Km, we can use the Michaelis-Menten equation, which relates the initial velocity of an enzyme to the substrate concentration and the enzyme's kinetic constants.

V0 = Vmax [S] / (Km + [S])

We can rearrange this equation to obtain a linear equation that can be used to determine Km.

1/V0 = (Km/Vmax) * (1/[S]) + 1/Vmax

We can plot 1/V0 against 1/[S] and determine the slope and y-intercept of the resulting line. The slope will be Km/Vmax, and the y-intercept will be 1/Vmax.

Using the given data, we can calculate the values of 1/V0 and 1/[S].

[S] (mM) V0 (μmol/min) 1/V0 1/[S]

1 167 0.0059 1

2 250 0.004 0.5

4 334 0.003 0.25

6 376 0.0027 0.167

10 498 0.002 0.1

100 498 0.002 0.01

1000 499 0.002 0.001

4981 499 0.002 0.0002

We can then plot 1/V0 against 1/[S] and obtain a linear regression line.

plot of 1/V0 vs. 1/[S]

The slope of the line is 0.0047, which is Km/Vmax. Therefore,

Km = slope * Vmax = 0.0047 * 499 = 2.34 mM

To determine the total amount of enzyme present in these experiments, we need to know the units of enzyme activity that were measured. Assuming that the enzyme activity was measured in μmol/min, we can use the definition of turnover number (kcat) to determine the total amount of enzyme present.

kcat = Vmax / [E]

where [E] is the concentration of enzyme in the reaction mixture.

From the given turnover number, kcat = 5000 min^-1. Therefore,

[E] = Vmax / kcat = 499 / 5000 = 0.0998 μM

To determine the total amount of enzyme present, we need to know the total volume of the reaction mixture. Let's assume that the total volume was 1 mL. Therefore,

Total enzyme = [E] * volume = 0.0998 μM * 1 mL * 1000 μmol/μM = 99.8 μmol

Therefore, the total amount of enzyme present in these experiments is 99.8 μmol.

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Twice.

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Answer:

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Explanation:

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Answer:

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Explanation:

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Answer:

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Explanation:

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The lineage of pea plants produced round seeds for four generations. The plants that fertilized these pea plants also produced round seeds. However, in the fifth generation, the plant produced to two plants with wrinkled seeds. Can that be possible? Explain your answer using your pedigree chart.​

Answers

Answer:

Explanation:

This happened because two fully recessive plants where introduced into the lineage. these plants where paired with the dominate verison. this would make all of the offspring have the two traits. this being said it would make it possible for the offspring to be Wrinkled Seeds.

When two heter0zyg0us individuals are crossed -simple d0minant inheritance-, or a heter0zyg0us individual is crossed with a h0m0zyg0us recessive one, they can produce h0m0zyg0us recessive subjects among the progeny. Heter0zyg0us individuals among the fourth generation got crossed with another plant (h0m0zyg0us recessive or heter0zyg0us) and produced two h0m0zyg0us recessive plants expressing wrinkle seeds.

---------------------------    

The first step is to understand the given information. So,

The first four generations produced round seedsPlants that fertilized these plants also produced round seeds (see generation II)  Among the fifth generation there are two plants with wrinkled seeds

Let us assume that a diallelic gene determines the shape of seeds.

D0minant allele R codes for round seedsRecessive allele r codes for wrinkle seeds

Now, let us analyze the pedigree. According to the information provided here, we can tell that

black figures represent h0m0zyg0us d0minant individuals, grey figures represent heter0zyg0us individualsempty figures represent h0m0zyg0us recessive individuals

Remember that Generations are represented with roman numbers.

We will name the plants with numbers from 1 to 26.

According to the information in the statement and the information in the pedigree, we can say that grey individuals from the fourth generation are heter0zyg0us expressing round seeds. They can produce wrinkle seeds, if they are fertilized by another heter0zyg0us plant or a h0m0zygous recessive one.

Option 1:

Two heter0zyg0us plants are crossed, and their offspring have wrinkled seeds.

Option 2:

One heter0zyg0us plant is crossed with a h0m0zyg0us recessive one, and their offspring have wrinkled seeds. Let us see the cross

Look at the attached files for a better understanding      

---------------------------------

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Answer:

assuming this is human it is 46

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PLEASE HELP ASAP Match each word with the phrase that best defines it.
informal
a statement that is objective or unchanging
fact
done in a way that is friendly or casual
formal
a statement that is subjective or based on
interpretation
topic
done in a way that is suitable, appropriate,
or based on guidelines
opinion
the main point of a given subject

Answers

Answer:

fact: a statement that is objective or unchanging

informal: done in a way that is friendly or casual

formal: done in a way that is suitable, appropriate,

or based on guidelines

opinion: a statement that is subjective or based on

interpretation

topic: the main point of a given subject

Match each word with the phrase that best defines it.

1. Fact: a statement that is objective or unchanging

2. Informal: done in a way that is friendly or casual

3. Formal: done in a way that is suitable, appropriate, or based on guidelines

4. Opinion: a statement that is subjective or based on interpretation

5. Topic: the main point of a given subject

What are Phrases?

A phrase is a group of words or a singular word which functions as a grammatical unit. For example, the English expression "the very happy boy" is a noun phrase containing the adjective phrase "very happy".

It can be a single word or a complete sentence. Phrases are used to describe the people, things, or events.

There are following types of phrases. They are:

Noun phrase.Adjective phrase.Adverb phrase.Verb phrase.Prepositional phrase.Gerund phraseInfinitive phraseParticipial phrase

Thus, matching the following words with its phrases

1. Fact: a statement that is objective or unchanging

2. Informal: done in a way that is friendly or casual

3. Formal: done in a way that is suitable, appropriate, or based on guidelines

4. Opinion: a statement that is subjective or based on interpretation

5. Topic: the main point of a given subject

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describe in on way in which the body gets rid of lactic acid

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lactic acid buildup is a harmless response to strenuous exercise and will go away on its own. Once the body has used the resulting lactate for energy, the liver breaks down any excess in the blood.

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Organic and healthy foods.

Oats, bananas, red meats, but STAY AWAY from drugs & alcohol!

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