what are two properties of hsp70 that are important for its chaperone function?

Answers

Answer 1

Two properties of Hsp70 that are important for its chaperone function are ATPase activity and Substrate binding domain.

Hsp70 has an intrinsic ATPase activity, which enables it to bind and hydrolyze ATP. This ATPase activity is crucial for the chaperone function of Hsp70 because it allows the protein to undergo conformational changes that enable it to bind and release substrate proteins. These conformational changes facilitate the proper folding or refolding of substrate proteins and prevent protein aggregation.

Hsp70 has a substrate binding domain that can recognize and bind to exposed hydrophobic regions on unfolded or partially folded proteins. This binding helps to stabilize the substrate proteins, preventing their aggregation and promoting their proper folding. The substrate binding domain is essential for Hsp70's chaperone function, as it allows the protein to interact with a wide variety of substrates and assist in their folding process.

In summary, the ATPase activity and substrate binding domain are two important properties of Hsp70 that contribute to its chaperone function, enabling it to prevent protein aggregation and facilitate proper protein folding.

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Related Questions

How was osmosis involved in the cause of Clark's seizures?

Answers

Answer:

after Clark was treated with a hypertonic solution? increased Na concentration in matrix of brain caused water from blood to move in to the brain which increased the matrix pressure. Pressure caused the neuron firing rate to increase which increased the likelihood of seizures.

What is an advantage of biofuels?

Answers

Answer:

Advantages of Biofuels Biofuels are considered a green alternative to conventional fuels, which means that they have more advantages than disadvantages. 1. Biofuels are renewable resources of energy

Explanation:

Why do you think eating beef and dairy from cows that are fed corn and soy has such a high environmental impact compared to eating vegetables?

Answers

Answer:

because it has more nutriants and helps them get fat more.

Explanation:

read it

What do you consider to be your culture? How do you feel about it?

Answers

Answer:

My culture is my Jewish culture.

Explanation:

I feel great about it.

PLEASE CHOOSE ALL 3 CORRECT ANSWERS! WILL MARK BRAINLIEST IF CORRECT

Which of the following are true of the transfer of thermal energy in the oceans? Select the three correct answers. (2 points)

Energy is absorbed more than radiated near the equator.

Energy is carried from the equator to poles in deep ocean currents.

Energy is carried from the equator to poles in surface currents.

Energy is radiated more than absorbed near the equator.

Energy is absorbed more than radiated near the poles.

Energy is radiated more than absorbed near the poles.

Answers

Answer:

Energy is absorbed more than radiated near the equator.

Energy is radiated more than absorbed near the poles.

Energy is absorbed more than radiated near the poles.

Describe at least two ways in which nitrogen is important to biological processes. (Hint: Find the biological chemicals that contain nitrogen.)

Answers

Answer:

Nitrogen is a crucially important component for all life. It is an important part of many cells and processes such as amino acids, proteins and even our DNA. It is also needed to make chlorophyll in plants, which is used in photosynthesis to make their food. Nitrogen is a key element in the nucleic acids DNA and RNA, which are the most important of all biological molecules and crucial for all living things.  Without amino acids, plants cannot make the special proteins that the plant cells need to grow. Without enough nitrogen, plant growth is affected negatively.

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Which best describes the flow of genetic information?

A) Genetic information flows from gene to allele to protein
B) Genetic information is carried only by DNA
C) Genetic information flows from DNA to RNA to protein
D) Genetic information cannot be transmitted outside the nucleus

Answers

Answer:

It’s c I got it right

Explanation:

Answer:

C) Genetic information flows from DNA to RNA to protein

Explanation:

DNA is an example of a nuclei case acid true or false

Answers

Answer:

The term nucleic acid is the overall name for DNA and RNA.

Explanation:

They are composed of nucleotides, which are the monomers made of three components: a 5-carbon sugar, a phosphate group and a nitrogenous base. ... The two main classes of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA).

Which stage of mitosis occurs the least often and why?

Answers

Explanation:

The Anaphase stage is the shortest phase of mitosis. During this phase, disjunction occurs, and migration of sister chromatids away from each other to the poles of the cell occurs, leading to the formation of daughter chromosomes. Molecular motors use ATP to shorten the spindle fibers attached to each sister chromatid

Explanation:

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.....

The pituitary gland is most similar to:
A A worker in a factory
B A mail carrier
C The boss of a big office
D A security guard or police officer

Answers

Answer:

C. The boss of a big office

Explanation:

It tells all the other hormones what to do

Have a great day!

In guinea pigs, white coat color is determined by the allele W. Black coat color is controlled by the allele w. Cross a white & black spotted pig with a black pig.

W = white

w = black

What percentage of the offspring will be black?

Answers

Answer:

About 75%

Explanation:

About 75% will have two ww alleles, while the rest will have Ww alleles.

75 percent I think that’s right

PLEASE HELP THE ASSIGNMENTS DUE TODAY
Which of the following statements about human population growth is TRUE?

(2 Points)

a. The population size is growing, and growth rate is increasing.

b. The population size is growing, and growth rate is decreasing.

c. The population size is decreasing, and growth rate is increasing.

d. None of these is true.

Answers

Answer:

The population size is growing, and growth rate is increasing

Answer: a

Explanation:

Question 1/7 The Nile River carries sediments to the ocean. Over time, the sediments are compressed as more sediments are deposited on top of them. Which type of rock will be formed?​

Answers

Answer:

Sedimentary Rock

Explanation:

Sedimentary rocks are formed from pieces of sediments or other existing organic matter or rock.

The sedimentary rock formation process begins with weathering which involves the breakdown of the sediments into small fragments. The next process is erosion, where water like the Nile River carries them to other places -  in this case, the Ocean.

Over time, the sediments settle and become compressed as more sediments are deposited on top of them.

This leads to the formation of Sedimentary Rocks.

In asexual reproduction, 2 parents each pass copies of all of their chromosomes to the offspring. true or false

Answers

Answer:

False.

Explanation:

Soil forms as ______ is broken down by weathering.

Group of answer choices

water

rock

humus

magma

Answers

Answer:

Humus

Explanation:

Humus is dark, organic material that forms in soil when plant and animal matter decays. When plants drop leaves, twigs, and other material to the ground, it piles up. This material is called leaf litter. When animals die, their remains add to the litter. Over time, all this litter decomposes

how many checkpoints are there in mitosis

Answers

Answer:

3

Explanation:

hope that helps!!!!!!!

Answer:

three

Explanation:

There are three major checkpoints in the cell cycle: one near the end of G1, a second at the G2/M transition, and the third during metaphase.

the greatest genetic variation in a species is found in a offspring that forms by...
A:Asexual Reproduction
B:Sexual Reproduction
C:Budding
D:Cell Division

Answers

B: Sexual Reproduction

a description of the forest ecosystem

Answers

A forest ecosystem is a natural woodland unit consisting of all plants, animals in micro organisms in that area functioning together with all nonliving physical factors of the environment. The forest ecosystem is very important

Four differences between viruses and bacteria​

Answers

Answer:

bacteria :

1. need microscope to see them.

2. need warmth moisture nutrients.

3. saprophyte or parasite.

4. can be harmful or useful.

viruses:

1. smaller than bacteria.

2. spend on living host.

3. always parasite.

4. where is harmful.

1. DNA 2. Helicase 3. DNA Polymerase 4. DNA Replication 5. Pyrimidine a. Double stranded molecule that has a deoxyribose sugar. b. The end-product of this process are two identical copies of DNA. c. Enzyme that breaks hydrogen bonds to unwind and unzip DNA. d. Nitrogen containing base that has a single ring as its molecular structure. Thymine and Cytosine are an example of this type of molecule. e. Enzyme that covalently bonds sugars and phosphates during DNA replication.

Answers

Answer:

1. DNA-A.Double stranded molecule that has a deoxyribose sugar.

2. Helicase- C. Enzyme that breaks hydrogen bonds to unwind and unzip DNA

3.DNA Polymerase- E. Enzyme that covalently bonds sugars and phosphates during DNA replication

4.DNA Replication-B. The end-product of this process are two identical copies of DNA.

5.Pyrimidine-D. Nitrogen containing base that has a single ring as its molecular structure. Thymine and Cytosine are an example of this type of molecule.

Explanation:

i have no idea about this

Answers

Answer:

I think it's 4 or 3

Explanation:

Sorry if I'm wrong

What does a mass extinction look like in the fossil record?​

Answers

There is less diversity hope this helps

Answer:

There is less diversity in the fossil record

Explanation: when compared to older rock layers the fossil record will be less diverse

A 154-lb adult man performs a moderate level of physical activity and regularly consumes 2700 Calories a day. State whether the weight of the man will most likely decrease, increase, or remain the same. Use information from the data table to explain your answer.

The weight of the man will...
Explanation...

Answers

Answer:

Increases.

Explanation:

A 154-lb adult man regularly consumes 2700 Calories a day and performs a moderate level of physical activity, the weight of that individual increases because a 154-lb adult man needs only 2450 Calories a day and that person consumes 2700 Calories a day which is higher than their needs so these extra calories stored in their body and as a result the weight of that person increases.

Firebreathing (F) is dominant in dragons. NON-firebreathing (f) is recessive.a)You have a firebreathing dragon. What are its possible genotypes

Answers

FF or Ff, since these traits that are displayed are the dominant ones these are the only possible genotypes for this dragon

How has technology such as telescopes, satellites, computers, and GPS units affect the scope of scientific discovery?

Answers

Answer:ghhjhjhkjhkjkjhkhExplanatio

Question 2 (1 point)
What type of Chemical bond holds the bases together?

a) Hydrogen bonds
b) Structural bonds
c) Nucleic bonds
d) Polar bonds

Answers

the answer is A, hope this helps !

PLS HELP I'LL GIVE THE BRAINLEST!!!
The lineage of pea plants produced round seeds for four generations. The plants that fertilized these pea plants also produced round seeds. However, in the fifth generation, the plant produced to two plants with wrinkled seeds. Can that be possible? Explain your answer using your pedigree chart.​

Answers

Answer:

Explanation:

This happened because two fully recessive plants where introduced into the lineage. these plants where paired with the dominate verison. this would make all of the offspring have the two traits. this being said it would make it possible for the offspring to be Wrinkled Seeds.

When two heter0zyg0us individuals are crossed -simple d0minant inheritance-, or a heter0zyg0us individual is crossed with a h0m0zyg0us recessive one, they can produce h0m0zyg0us recessive subjects among the progeny. Heter0zyg0us individuals among the fourth generation got crossed with another plant (h0m0zyg0us recessive or heter0zyg0us) and produced two h0m0zyg0us recessive plants expressing wrinkle seeds.

---------------------------    

The first step is to understand the given information. So,

The first four generations produced round seedsPlants that fertilized these plants also produced round seeds (see generation II)  Among the fifth generation there are two plants with wrinkled seeds

Let us assume that a diallelic gene determines the shape of seeds.

D0minant allele R codes for round seedsRecessive allele r codes for wrinkle seeds

Now, let us analyze the pedigree. According to the information provided here, we can tell that

black figures represent h0m0zyg0us d0minant individuals, grey figures represent heter0zyg0us individualsempty figures represent h0m0zyg0us recessive individuals

Remember that Generations are represented with roman numbers.

We will name the plants with numbers from 1 to 26.

According to the information in the statement and the information in the pedigree, we can say that grey individuals from the fourth generation are heter0zyg0us expressing round seeds. They can produce wrinkle seeds, if they are fertilized by another heter0zyg0us plant or a h0m0zygous recessive one.

Option 1:

Two heter0zyg0us plants are crossed, and their offspring have wrinkled seeds.

Option 2:

One heter0zyg0us plant is crossed with a h0m0zyg0us recessive one, and their offspring have wrinkled seeds. Let us see the cross

Look at the attached files for a better understanding      

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Which statement is true regarding mitosis?
A. 2 cells are made from one cell
B. daughter cells have 1/2 of the original DNA
C. occurs only in sex cells
D. 4 cells are made from one cell.

Answers

Answer:

A. 2 cells are made from one cell

which of the following is a stimulus, which response?
A. The recess bell ringing in a elementary school
B. Your mouth watering at sight of food on a plate
C. A sudden drop in air temperature
D. A flu virus entering your body
E. Getting "butterflies" in your stomach before giving a speech

Answers

Answer:

A. Stimulus

B. Response

C. Stimulus

D. Stimulus

E. Response

Explanation:

It's forensic science

Answers

Answer: Loops: 65%, whorls: 30%, and arches: 5%

Explanation:

The loops are 65% in the population, 30% are whorls and arches are 5%. The fingerprints are the patterns which include the friction ridge characteristics also called minutiae characteristics. These can be found in the soles of feet and palms of hand. At the distal end of finger the typical friction ridge pattern forms patterns like loops, whorls, arches, and composites which are patterns including two or more patterns. The loops are most common in the population the ridges emerge and end on the same side in this pattern. The loops are radial or ulnar loops depending upon the side in which pattern ends of the side of the bone thumb in case of radial and little finger in case of ulnar loop.

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Douglas MacArthur was the commander of U.S. Army forces in Asia.TrueFalse 1. In the expression x2, 2 is what we callA. BaseB. ExponentC. Multiple A. If 15 ml of a liquid has a mass of 11.85 grams,(1) What is the density?(2) What is the liquid? In the story Oscars Wilde play What is the meaning of the word earnest in this scene?honestdecitfulrudea man's name A 30-year-old male demonstrated a subtle onset of the following symptoms: dull facial expression; droopy eyelids; puffiness of the face and periorbital swelling; sparse, dry hair; dry, scaly skin; evidence of intellectual impairment; lethargy; a change of personality; bradycardia (60 b/min) low range of normal; a blood pressure of 90/70 low BP; anemia low iron cant transport O through body very well(hematocrit 27); enlarged heart (upon radiological exam); constipation, and hypothermia. Plasma concentrations of total and free T4 and T3 follow:Radioimmunoassay (RIA) of peripheral blood indicated elevated TSH levels. A TSH stimulation test did not increase the output of thyroid hormones from the thyroid gland. a. What endocrine organ is involved here? b. Is this a primary or secondary disorder? Why? (Is a TSH or TRH determination necessary for your diagnosis?) c. Describe the feedback loop involved, indicating if there is an increased or decreased TSH level. d. List several defects that could cause these symptoms. e. Would you expect to find a palpable goiter? Explain your answer. f. Describe a suitable treatment for this individual. Question 2 of 10Which of the following statements is true? Find the value of the expression below for x=3 x^2+5 Why did more volunteers join the militias after the battles of Lexington and Concord?Someone help please Find the value of x.x + 312 whats the primarry reason for a diffrence in climate between new york and florida A man of letters as a man of business summary please? HELP ME!! I have 1 hour left before I pass it but Im horrible in writing reflections, Please help!Write a reflection in accomplishing your physical activity program. (3-5 Sentences only)The program was about working out or exercising like jumping rope, biking, dancing, etc Students want to see if plants need sunlight to grow. They have 4 plants that are all the same kind. They put 2 of them in a sunny window. Where should the other 2 plants be placed? Answer options with 4 options a. In a kitchen b. In a dark closet c. Near a fireplace d. In a different window When two substances combine to form a mixture, the properties of the substances change. True False Can someone plz help me with this? Two organisms that share several classifications level's will be Which number is NOT in the solution set of the inequality x < 15?A)0B)5C)10D)20 Diseases from the present age is different from diseases of the past. Discuss I need help with this What qualifications did Jefferson have to serve on Washington's cabinet?